Our Latest Research
Check out our lab latest publications and academic presentations.


Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement from the American Heart Association and Neurocritical Care Society. Circulation. 2024 Jan 9;149(2):e168-e200. Hirsch KG, Abella BS, Amorim E, Bader MK, Barletta JF, Berg K, Callaway CW, Friberg H, Gilmore EJ, Greer DM, Kern KB, Livesay S, May TL, Neumar RW, Nolan JP, Oddo M, Peberdy MA, Poloyac SM, Seder D, Taccone FS, Uzendu A, Walsh B, Zimmerman JL, Geocadin RG; American Heart Association, Neurocritical Care Society. doi: 10.1161/CIR.0000000000001163. Epub 2023 Nov 28. PMID: 38014539; PMCID: PMC10775969.


Mortality and Timing of Withdrawal of Life-Sustaining Therapies After Out-of-Hospital Cardiac Arrest: Two-Center Retrospective Pediatric Cohort Study. Pediatr Crit Care Med. 2023 Nov 20. Vassar R, Mehta N, Epps L, Jiang F, Amorim E, Wietstock S. doi: 10.1097/PCC.0000000000003412. Epub ahead of print. PMID: 37982686.


A quantitative EEG index for the recognition of arterial ischemic stroke in children. Clin Neurophysiol. 2023 Dec;156:113-124. Caffarelli M, Karukonda V, Aghaeeaval M, McQuillen PS, Numis AL, Mackay MT, Press CA, Wintermark M, Fox CK, Amorim E; SIPS Investigators. doi: 10.1016/j.clinph.2023.10.001. Epub 2023 Oct 11. PMID: 37918222.


The International Cardiac Arrest Research Consortium Electroencephalography Database. Crit Care Med. 2023 Dec 1;51(12):1802-1811. Amorim E, Zheng WL, Ghassemi MM, Aghaeeaval M, Kandhare P, Karukonda V, Lee JW, Herman ST, Sivaraju A, Gaspard N, Hofmeijer J, van Putten MJAM, Sameni R, Reyna MA, Clifford GD, Westover MB. doi: 10.1097/CCM.0000000000006074. Epub 2023 Oct 19. PMID: 37855659; PMCID: PMC10841086.



Predicting neurological recovery from coma after cardiac arrest: The George B. Moody PhysioNet Challenge 2023. Computing in Cardiology, 2023, 50, 1-4. Reyna MA*, Amorim E*, Sameni R, Weigle J, Elola A, Bahrami Rad A, Seyedi S, Kwon H, Zheng WL, Ghassemi MM, van Putten MJAM, Hofmeijer J, Gaspard N, Sivaraju A, Herman ST, Lee JW, Westover MB, Clifford GD.*Co-first authors.


Increased task-relevant fMRI responsiveness in comatose cardiac arrest patients is associated with improved neurologic outcomes. J Cereb Blood Flow Metab. 2024 Jan;44(1):50-65.Dhakal K, Rosenthal ES, Kulpanowski AM, Dodelson JA, Wang Z, Cudemus-Deseda G, Villien M, Edlow BL, Presciutti AM, Januzzi JL, Ning M, Taylor Kimberly W, Amorim E, Brandon Westover M, Copen WA, Schaefer PW, Giacino JT, Greer DM, Wu O. doi: 10.1177/0271678X231197392. Epub 2023 Sep 20. PMID: 37728641.


Practice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process. Crit Care Med. 2023 Dec 1;51(12):1740-1753. Foreman B, Kapinos G, Wainwright MS, Ngwenya LB, O'Phelan KH, LaRovere KL, Kirschen MP, Appavu B, Lazaridis C, Alkhachroum A, Maciel CB, Amorim E, Chang JJ, Gilmore EJ, Rosenthal ES, Park S. doi: 10.1097/CCM.0000000000006016. Epub 2023 Nov 16. PMID: 37607072.


Neurophysiology State Dynamics Underlying Acute Neurologic Recovery After Cardiac Arrest. Neurology. 2023 Aug 29;101(9):e940-e952. doi: Amorim E, Zheng WL, Jing J, Ghassemi MM, Lee JW, Wu O, Herman ST, Pang T, Sivaraju A, Gaspard N, Hirsch L, Ruijter BJ, Tjepkema-Cloostermans MC, Hofmeijer J, van Putten MJAM, Westover MB. 10.1212/WNL.0000000000207537. Epub 2023 Jul 6. PMID: 37414565.



Post-cardiac arrest Sedation Promotes Electroencephalographic Slow-wave Activity and Improves Survival in a Mouse Model of Cardiac Arrest. Anesthesiology. 2022 Dec 1;137(6):716-732. Ikeda T, Amorim E, Miyazaki Y, Kato R, Marutani E, Silverman MG, Malhotra R, Solt K, Ichinose F. doi: 10.1097/ALN.0000000000004390. PMID: 36170545

Neurocritical Care Performance Measures Derived from Electronic Health Record Data are Feasible and Reveal Site-Specific Variation: A CHoRUS Pilot Project. Neurocrit Care. 2022 08; 37(Suppl 2):276-290.Ack SE, Loiseau SY, Sharma G, Goldstein JN, Lissak IA, Duffy SM, Amorim E, Vespa P, Moorman JR, Hu X, Clermont G, Park S, Kamaleswaran R, Foreman BP, Rosenthal ES.  PMID: 35689135.


Geometric and Morphologic Features of Ruptured Intracranial Aneurysms Associated with Methamphetamine Use. World Neurosurg. 2022 08; 164:e509-e517.Caton MT, Vitt J, Smith ER, Cooke D, Meisel K, Ko N, Amorim E.  PMID: 35552027.


Reply to "Continuous EEG in patients with extracorporeal membrane oxygenation support: Clinical need in multidisciplinary collaboration and standardized monitoring". Clin Neurophysiol. 2022 Oct;142:275-276. Amorim E, Westover MB. doi: 10.1016/j.clinph.2022.07.488. Epub 2022 Jul 26. PMID: 35933303.




High incidence of epileptiform activity in adults undergoing extracorporeal membrane oxygenation. Clin Neurophysiol. 2022 08; 140:4-11. Amorim E, Firme MS, Zheng WL, Shelton KT, Akeju O, Cudemus G, Yuval R, Westover MB.  PMID: 35691268; PMCID: PMC9340813.




Predicting Neurological Outcome From Electroencephalogram Dynamics in Comatose Patients After Cardiac Arrest With Deep Learning. IEEE Trans Biomed Eng. 2022 05; 69(5):1813-1825.Zheng WL, Amorim E, Jing J, Wu O, Ghassemi M, Lee JW, Sivaraju A, Pang T, Herman ST, Gaspard N, Ruijter BJ, Tjepkema-Cloostermans MC, Hofmeijer J, van Putten MJAM, Westover MB.  PMID: 34962860.



Expert-augmented automated machine learning optimizes hemodynamic predictors of spinal cord injury outcome. PLoS One. 2022; 17(4):e0265254.Chou A, Torres-Espin A, Kyritsis N, Huie JR, Khatry S, Funk J, Hay J, Lofgreen A, Shah R, McCann C, Pascual LU, Amorim E, Weinstein PR, Manley GT, Dhall SS, Pan JZ, Bresnahan JC, Beattie MS, Whetstone WD, Ferguson AR, TRACK-SCI Investigators.  PMID: 35390006.


Perceptions of Critical Care Shortages, Resource Use, and Provider Well-being During the COVID-19 Pandemic: A Survey of 1,985 Health Care Providers in Brazil. Chest. 2022 06; 161(6):1526-1542.Lobo SM, Creutzfeldt CJ, Maia IS, Town JA, Amorim E, Kross EK, Çoruh B, Patel PV, Jannotta GE, Lewis A, Greer DM, Curtis JR, Sharma M, Wahlster S.  PMID: 35150658.


Severe cerebral edema in substance-related cardiac arrest patients. Resuscitation. 2022 04; 173:103-111.Kulpanowski AM, Copen WA, Hancock BL, Rosenthal ES, Schoenfeld DA, Dodelson JA, Edlow BL, Kimberly WT, Amorim E, Westover MB, Ning MM, Schaefer PW, Malhotra R, Giacino JT, Greer DM, Wu O.  PMID: 35149137.



Regional Distribution of Brain Injury After Cardiac Arrest: Clinical and Electrographic Correlates. Neurology. 2022 03 22; 98(12):e1238-e1247.Snider SB, Fischer D, McKeown ME, Cohen AL, Schaper FLWVJ, Amorim E, Fox MD, Scirica B, Bevers MB, Lee JW.  PMID: 35017304; PMCID: PMC8967331.



Predicting neurological outcome in comatose patients after cardiac arrest with multiscale deep neural networks. Resuscitation. 2021 12; 169:86-94.Zheng WL, Amorim E, Jing J, Ge W, Hong S, Wu O, Ghassemi M, Lee JW, Sivaraju A, Pang T, Herman ST, Gaspard N, Ruijter BJ, Sun J, Tjepkema-Cloostermans MC, Hofmeijer J, van Putten MJAM, Westover MB.  PMID: 34699925.



A Global Survey of the Effect of COVID-19 on Critical Care Training. ATS Sch. 2021 Dec; 2(4):508-520.Wahlster S, Sharma M, Çoruh B, Town JA, Lewis A, Lobo SM, Maia IS, Hartog C, Patel PV, Kross EK, Amorim E, Greer DM, Curtis JR, Creutzfeldt CJ.  PMID: 35083459; PMCID: PMC8787747.




A Matter of Timing: EEG Monitoring for Neurological Prognostication After Cardiac Arrest in the Era of Targeted Temperature Management. Minerva Anestesiologica. 2020. Khazanova, D, Douglas, V., Amorim, E. PMID: 33591136.





Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies. Neurocritical Care. 2020 Sep 21. Simpkins A, Busl KM, MD, Amorim E, Barnett-Tapia C, Cervenka M, Dhakar MB, Etherton ME, Fung C, Griggs R, Holloway RG, Kelly AG, Khan IR, Lizarraga K, Madagan HG, Onweni CL, Mestre H, Rabinstein AA, Rubinos C, Dionisio-Santos DA, Youn TS, Merck LH, Maciel. PMID: 32959201.



Cost-effectiveness analysis of multimodal prognostication in cardiac arrest with EEG monitoring. Neurology. 2020 Jul 13. Amorim E, Mo SS, Palacios S, Ghassemi MM, Weng WH, Cash SS, Bianchi MT, Westover MB.  PMID: 32661097.




A standardized nomenclature for spectrogram EEG patterns: Inter-rater agreement and correspondence with common intensive care unit EEG patterns. Clin Neurophysiol. 2020 Jun 24. Zafar SF, Amorim E, Williamsom CA, Jing J, Gilmore EJ, Haider HA, Swisher C, Struck A, Rosenthal ES, Ng M, Schmitt S, Lee JW, Brandon Westover M.  PMID: 32660817.



MRI-EEG correlation for outcome prediction in postanoxic myoclonus: A multicenter study. Neurology. 2020 Jun 01. Beuchat I, Sivaraju A, Amorim E, Gilmore EJ, Dunet V, Rossetti AO, Westover MB, Hsu L, Scirica BM, Silva D, Tang K, Lee JW.  PMID: 32482841.




A theoretical paradigm for evaluating risk-benefit of status epilepticus treatment. Journal of Clinical Neurophysiology. September 2020 37(5): 385-392. Amorim E, McGraw, C, Westover MB. PMCI7516305.




2019 and earlier

Quantitative Electroencephalogram Trends Predict Recovery in Hypoxic-Ischemic Encephalopathy. Crit Care Med. 2019 10; 47(10):1416-1423. Ghassemi MM, Amorim E, Alhanai T, Lee JW, Herman ST, Sivaraju A, Gaspard N, Hirsch LJ, Scirica BM, Biswal S, Moura Junior V, Cash SS, Brown EN, Mark RG, Westover MB.  PMID: 31241498.

Quantitative EEG reactivity and machine learning for prognostication in hypoxic-ischemic brain injury. Clin Neurophysiol. 2019 10; 130(10):1908-1916. Amorim E, van der Stoel M, Nagaraj SB, Ghassemi MM, Jing J, O'Reilly UM, Scirica BM, Lee JW, Cash SS, Westover MB.  PMID: 31419742.

Smaller left anterior cingulate cortex in non-bipolar relatives of patients with bipolar disorder. Braz J Psychiatry. 2019 May-Jun; 41(3):254-256. Sanches M, Amorim E, Mwangi B, Zunta-Soares GB, Soares JC.  PMID: 30540025.

Estimating the False Positive Rate of Absent Somatosensory Evoked Potentials in Cardiac Arrest Prognostication. Crit Care Med. 2018 12; 46(12):e1213-e1221. Amorim E, Ghassemi MM, Lee JW, Greer DM, Kaplan PW, Cole AJ, Cash SS, Bianchi MT, Westover MB.  PMID: 30247243.

EEG Reactivity Evaluation Practices for Adult and Pediatric Hypoxic-Ischemic Coma Prognostication in North America. J Clin Neurophysiol. 2018 Nov; 35(6):510-514. Amorim E, Gilmore EJ, Abend NS, Hahn CD, Gaspard N, Herman ST, Hirsch LJ, Lee JW, Cash SS, Westover MB.  PMID: 30216207.

Performance of Spectrogram-Based Seizure Identification of Adult EEGs by Critical Care Nurses and Neurophysiologists. J Clin Neurophysiol. 2017 Jul; 34(4):359-364. Amorim E, Williamson CA, Moura LMVR, Shafi MM, Gaspard N, Rosenthal ES, Guanci MM, Rajajee V, Westover MB.  PMID: 27930420.

Continuous EEG monitoring enhances multimodal outcome prediction in hypoxic-ischemic brain injury. Resuscitation. 2016 12; 109:121-126. Amorim E, Rittenberger JC, Zheng JJ, Westover MB, Baldwin ME, Callaway CW, Popescu A.  PMID: 27554945.

Rapidly-progressive catatonia responsive to zolpidem in a patient with ovarian teratoma-associated paraneoplastic encephalitis. J Clin Neurosci. 2016 Aug; 30:136-138. Amorim E, McDade EM.  PMID: 26964475.

Malignant EEG patterns in cardiac arrest patients treated with targeted temperature management who survive to hospital discharge. Resuscitation. 2015 May; 90:127-32. Amorim E, Rittenberger JC, Baldwin ME, Callaway CW, Popescu A.  PMID: 25779006.

An enhanced cerebral recovery index for coma prognostication following cardiac arrest. Conf Proc IEEE Eng Med Biol Soc. 2015; 2015:534-7. Ghassemi MM, Amorim E, Pati SB, Mark RG, Brown EN, Purdon PL, Westover MB.  PMID: 26736317.

Outcomes after endovascular treatment for anterior circulation stroke presenting as wake-up strokes are not different than those with witnessed onset beyond 8 hours. J Neurointerv Surg. 2015 Dec; 7(12):875-80. Aghaebrahim A, Leiva-Salinas C, Jadhav AP, Jankowitz B, Zaidi S, Jumaa M, Urra X, Amorim E, Zhu G, Giurgiutiu DV, Horev A, Reddy V, Hammer M, Wechsler L, Wintermark M, Jovin T.  PMID: 25326003.

Recovery from ophthalmoplegia and proptosis after repair of bilateral carotid-cavernous sinus fistulas. JAMA Neurol. 2013 Dec; 70(12):1584-5. Amorim E, Jankowitz BT, Jovin TG, Jadhav AP.  PMID: 24322514.

Impact of telemedicine implementation in thrombolytic use for acute ischemic stroke: the University of Pittsburgh Medical Center telestroke network experience. J Stroke Cerebrovasc Dis. 2013 May; 22(4):527-31. Amorim E, Shih MM, Koehler SA, Massaro LL, Zaidi SF, Jumaa MA, Reddy VK, Hammer MD, Jovin TG, Wechsler LR.  PMID: 23489955.

Spine trauma due to diving: main features and short-term neurological outcome. Spinal Cord. 2011 Feb; 49(2):206-10. Amorim E, Vetter H, Mascarenhas LB, Gomes EG, Carvalho JB, Gomes JF.  PMID: 20625383.


This work has been generously supported by: